Revance Products: Complete Guide for Aesthetic Practices

Key Takeaways

• Revance is an aesthetics and skincare company formed through Crown Laboratories' acquisition of Revance Therapeutics in February 2025, creating a comprehensive portfolio spanning neuromodulators, dermal fillers, and medical devices.
• DAXXIFY is an FDA-approved neuromodulator, receiving approval in September 2022 for the temporary improvement in the appearance of moderate to severe glabellar lines in adults.
• The RHA Collection consists of FDA-approved hyaluronic acid fillers made by TEOXANE in Switzerland using Preserved Network Technology; RHA 2, RHA 3, and RHA 4 are approved for moderate to severe dynamic facial wrinkles and folds in adults aged 22 or older.
• Portrait is a marketplace for licensed practices with national-account pricing.

By Khadija Sukhera, Barrister, Lincoln's Inn · Medically reviewed by Patrick Blake, MD, FAAD · Last updated 2026-10-16

Revance is an aesthetics and skincare company whose product portfolio includes DAXXIFY, the RHA Collection, SkinPen, and skincare brands. For a licensed practice evaluating Revance products, the buying decision involves product indications, wholesale costs, supplier terms, and staff readiness. Start with the category you need, then compare acquisition costs with your practice's pricing and demand.

What is Revance, and who owns Revance Therapeutics?

Crown Laboratories acquired Revance Therapeutics in February 2025, bringing its skincare and device portfolio together with Revance's injectables. The combination connects products across categories, but your purchasing decision still needs a product-by-product review.

Crown Laboratories announced the completed acquisition on February 6, 2025, in its acquisition announcement. This followed the August 2024 merger announcement, which proposed an acquisition worth approximately $924 million.

Revance Therapeutics began in 1999 as Essentia Biosystems, a Silicon Valley biotechnology company. DAXXIFY received FDA approval in September 2022 for the temporary improvement in the appearance of moderate to severe glabellar lines in adults. Following the acquisition, the combined company operates under the Revance name, with corporate headquarters in Nashville, Tennessee.

The combined business has distribution spanning 60 countries. Crown's backing from Hildred Capital Management is part of that ownership background. For your clinic, review the product portfolio alongside supplier terms, local demand, and the training your team needs.

In May 2025, Revance announced that Nadeem Moiz would succeed founder Jeff Bedard as CEO effective October 1, 2025, with Bedard becoming Executive Chairman.

Which Revance products should a practice compare?

Revance's portfolio covers neuromodulators, hyaluronic acid dermal fillers, microneedling devices, and skincare. Compare each category separately because acquisition costs include different items: injectable inventory, device equipment and cartridges, or skincare stock.

Use this category map to decide which products deserve a detailed quote. A clinic refining an injectable menu has a different purchasing brief from a clinic considering equipment or adding skincare inventory. Start with your service focus and patient demand, then review the relevant products below.

DAXXIFY: manufacturer, approval, and vial sizes

DAXXIFY is Revance's neuromodulator, manufactured in the United States. Its cosmetic approval dates to September 2022, and approval for cervical dystonia followed in August 2023.

DAXXIFY is indicated in adults for the temporary improvement in the appearance of moderate to severe glabellar lines associated with corrugator and/or procerus muscle activity, and for the treatment of cervical dystonia (DAXXIFY prescribing information). Keep your product review tied to those indications and the clinician's scope of practice.

DAXXIFY comes in single-dose vials containing 50 Units or 100 Units (DAXXIFY vial specifications). Record the vial size alongside each supplier quote when reviewing acquisition costs. Evaluate storage and staff training as part of the same purchasing decision.

The SAKURA Phase 3 clinical program enrolled more than 2,700 patients, who received approximately 4,200 treatments.

RHA Collection: manufacturer and formulations

TEOXANE SA in Switzerland manufactures the RHA Collection, which Revance distributes in the United States. TEOXANE was founded in 2003. The collection includes RHA 2, RHA 3, RHA 4, and RHA Redensity; the manufacturer uses Preserved Network Technology.

RHA 2, RHA 3, and RHA 4 are approved to correct moderate to severe dynamic facial wrinkles and folds, such as nasolabial folds, in adults aged 22 years or older. Consult the RHA product labeling as part of the clinical review. RHA Redensity is approved to correct moderate to severe dynamic perioral rhytids, or lip lines, and RHA 3 is also approved for lip augmentation and lip fullness, in adults aged 22 years or older.

Keep the individual formulation visible in both your service planning and purchasing records. The collection name alone does not identify which product you intend to order. Ask the clinical team to identify the relevant formulation before requesting pricing, and assess the quote against that selection.

RHA syringes contain 1 mL per syringe. Wholesale costs vary by formulation and volume agreements. List the formulation on each quote so your cost review stays tied to the product you plan to stock.

SkinPen: device history and operating considerations

SkinPen Precision joined the Revance portfolio through Crown Aesthetics.

SkinPen Precision is cleared to improve the appearance of facial acne scars in adults aged 22 years and older with all Fitzpatrick skin types, and the appearance of neck wrinkles in Fitzpatrick skin types II to IV; the neck-wrinkle clearance dates to 2021. A SkinPen session takes approximately 30 minutes.

Crown Aesthetics launched SkinPen Precision Elite in December 2024. Its equipment features include RFID cartridges and active retraction technology called ActiSine. The device comes with a lifetime warranty; review the warranty terms with the supplier before purchase.

SkinPen Precision also carries CE marking. Review the documentation for the exact model you are considering, including its indication and equipment terms, before completing the purchase.

Device economics include the equipment purchase and ongoing cartridge expenses. Ask for those costs separately when comparing quotes, then include staff training and appointment time in your practice budget.

Skincare within the combined portfolio

The combined skincare portfolio includes PanOxyl, Blue Lizard, StriVectin, and BIOJUVE. PanOxyl includes acne-treatment products, and Blue Lizard offers mineral sunscreens. Review the skincare assortment against the products your practice already recommends and sells.

Keep the retail-stock decision focused on your clinic's patient relationships beyond treatment appointments. Consider which brands fit the service menu, how your staff will explain the selection, and what inventory you want to carry. Assess skincare alongside the rest of your product mix without assuming you need every category.

How much do Revance products cost wholesale and retail?

Formulation, volume agreements, and supplier relationships affect the quote you receive.

Request supplier pricing for the vial size and order quantity you intend to buy.

Build your margin review around acquisition cost, local retail pricing, expected volume, storage, and training. Keep equipment purchases separate from recurring supplies so you can see what you must fund before launch and what you will reorder.

For each injectable product, compare supplier terms against realistic patient demand. Review the volume needed to access favorable pricing and whether your clinic expects that demand. Use local competitor pricing as context for your own service menu, alongside the cost of delivering the service.

Revisit supplier relationships quarterly. Review purchasing patterns and discuss terms as your order volume changes. Monitor wholesale pricing stability over 3 to 6 months before making a larger inventory commitment.

Are Revance products FDA-approved, and who can use them?

DAXXIFY and the RHA fillers have FDA approvals, while SkinPen Precision has FDA clearance; check your state board's practitioner requirements for each treatment. Review the product's regulatory documentation and your team's scope before adding it to the menu.

For device classification, microneedling devices for aesthetic use fall under Class II (special controls) in 21 CFR 878.4430. The classification does not include devices intended for transdermal delivery of topical products such as cosmetics, drugs, or biologics.

Check your state board's requirements for the clinician who will provide each service and any supervision arrangements. Include medical director oversight in that review where applicable. Confirm the requirements for your location before assigning injectable or microneedling appointments to staff.

Include storage and handling in your purchasing checklist. Unopened DAXXIFY vials may be stored at room temperature 20 to 25°C (68 to 77°F) or refrigerated at 2 to 8°C (36 to 46°F), in the original carton to protect from light. Check product-specific storage instructions before delivery, retain original packaging, and track lot numbers for traceability. Build staff training into the same review so the purchasing decision reflects the operational work involved.

Which alternatives to Revance products should you compare?

BOTOX Cosmetic (onabotulinumtoxinA), Dysport (abobotulinumtoxinA), and Jeuveau (prabotulinumtoxinA) are neuromodulator alternatives, while Restylane and JUVÉDERM offer filler alternatives. Compare your existing manufacturer relationships, local brand demand, acquisition costs, and training needs before changing your product mix.

Ask for the product and pack details on each quote, then assess the pricing against your clinic's planned inventory and local service pricing.

For fillers, review the Restylane and JUVÉDERM comparison alongside your RHA options. Restylane belongs to Galderma's portfolio; JUVÉDERM belongs to Allergan/AbbVie. Existing manufacturer agreements and patient requests may influence which portfolio you choose to stock.

JUVÉDERM uses VYCROSS technology in some formulations. Include the specific formulation in your comparison of filler options and ask your clinical team to review its indication before you make the inventory decision.

A single-manufacturer approach may suit your existing relationships and training preferences. A broader product mix may suit a clinic with demand across categories. Choose the approach after reviewing your own patient requests and staff capacity, then review the supplier terms against that plan.

How should you choose Revance products for your practice?

Choose Revance products by matching your service focus and patient demand to acquisition costs, staff expertise, and training capacity. Product selection works best as a purchasing review tied to your clinic's actual operations.

1. Define the service focus. Decide whether you want to refine an injectable menu, add a device service, or expand skincare retail. Consider your patient demographic and the expertise already available in the practice.
2. Review local demand. Check competitor websites and the brands patients request. Decide how much product education your team can support before introducing another option.
3. Build the cost picture. Request supplier quotes and include storage, ongoing supplies, and staff training in the budget. Compare these costs with your expected volume and local retail pricing.
4. Plan the introduction. Train staff before adding the service and track retention and repeat bookings after launch. Review purchasing patterns before expanding your inventory commitment.

Use the review to decide how broad your initial product mix should be. A practice with limited training capacity may prefer familiar products; a clinic expanding its menu should account for the staff preparation involved. Keep your selection tied to the services you intend to offer and the demand you can support.

How does Portrait fit into your supply purchasing?

Portrait is a marketplace for licensed practices with national-account pricing. Use your product shortlist and purchasing requirements when reviewing supply pricing for your practice.

Core EHR is complimentary with Portrait membership, and members join through the pre-load. Compare your purchasing needs with the membership model as part of your broader practice budget.

See your supply pricing

Frequently asked questions

These answers cover Revance's company background, DAXXIFY manufacturing, filler products, and SkinPen's place in the portfolio.

What is Revance?

Revance is an aesthetics and skincare company with injectables, microneedling devices, and skincare in its portfolio. Its products include DAXXIFY, the RHA Collection, and SkinPen. For your practice, evaluate the relevant product category alongside supplier terms, local demand, and the staff training needed to introduce it.

Who owns Revance Therapeutics?

Crown Laboratories acquired Revance Therapeutics in February 2025. The acquisition brought Revance's injectables together with Crown's skincare and device portfolio. For a practice owner reviewing the combined business, compare the products you want to stock and their supplier terms before making a broader purchasing commitment.

Who makes DAXXIFY?

Revance makes DAXXIFY, and the product is manufactured in the United States. Crown Laboratories acquired Revance Therapeutics in February 2025. When evaluating DAXXIFY for your practice, review the labeled indications, vial size, supplier pricing, and your team's licensing and training requirements before placing an order.

What fillers does Revance offer?

Revance distributes the TEOXANE RHA Collection in the United States, which includes RHA 2, RHA 3, RHA 4, and RHA Redensity. TEOXANE SA in Switzerland manufactures the collection. Compare the specific formulation and its labeling when selecting inventory, then request a quote that reflects your intended product mix and purchasing volume.

Is SkinPen part of Revance?

SkinPen is part of the Revance portfolio through Crown Aesthetics. The range includes SkinPen Precision and SkinPen Precision Elite. For your purchasing review, separate the device cost from ongoing cartridge expenses and include staff training and appointment capacity when deciding whether to add the service.

Savings vary by practice, product mix, and order volume. Figures reflect select products and are not guaranteed.

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