Prollenium Medical Technologies Products: Complete Guide for Aesthetic Practices

Key Takeaways

• Prollenium is the only HA filler manufacturer in North America, producing the Revanesse line (Versa, Versa+, Lips+, Ultra) with FDA approvals for facial wrinkles, folds, and lip augmentation.
• Revanesse Versa offers a value advantage with its 1.2 mL syringe size versus competitors' 1.0 mL syringes, with results typically lasting 6–12 months.
• Wholesale costs range from $240–$350 per syringe while retail pricing sits at $500–$700, creating strong margins for practices with volume-based purchasing.
• Portrait Care helps clinics maximize filler profitability through national pricing power, operational support, and integrated practice management tools.

Prollenium Medical Technologies is a Canadian-based aesthetics company founded in 2002, specializing in hyaluronic acid dermal fillers and aesthetic injection products, all researched, designed, manufactured, and distributed in-house. The flagship Revanesse line is one of the fastest-growing dermal filler portfolios in North America, produced in small batches with rigorous quality control at Canada's first dedicated dermal filler manufacturing facility.

All core Revanesse products are FDA-approved or cleared, with Revanesse Versa receiving Premarket Approval in August 2017 for the correction of moderate to severe facial wrinkles and folds, and subsequent approvals for Ultra and Lips+ expanding the line's indications. Typical retail pricing ranges from about $500–$700 per syringe for hyaluronic acid fillers like Versa and Lips+, while wholesale costs for HA fillers generally fall in the $240–$350 range per syringe, creating attractive margins when your purchasing volume qualifies you for preferred pricing tiers.

Revanesse fillers are formulated with highly refined, homogenous hyaluronic acid gels that integrate smoothly into tissue, enabling providers to customize treatment plans for nasolabial folds, lips, midface volume, and fine lines using different products within the portfolio (Versa/Versa+, Lips+, Ultra, and other global SKUs). Portrait Care helps clinics source Revanesse and other injectables with national pricing power, tiered discounts, and integrated operational support so that premium fillers translate into sustainable profitability.

About Prollenium Medical Technologies

When patients ask for "Versa" or "Revanesse lips" by name, they are referring to products from Prollenium Medical Technologies, a Canadian aesthetics company dedicated exclusively to injectable HA fillers and related technologies since 2002. Ario Khoshbin founded Prollenium with a small loan and initially focused on distributing aesthetic laser devices before shifting to in-house HA filler development and manufacturing by 2008.

By 2011, Prollenium opened the first dermal filler manufacturing facility in Canada, bringing all R&D and production under one roof to maintain tight quality standards and oversight of every syringe. The company's mission is to provide innovative, safe, and viable implantable polymers for aesthetic medicine, with Revanesse now available in markets including the United States, Canada, and the United Kingdom.

Today, Prollenium remains the only manufacturer of HA dermal fillers in North America, a strategic advantage that supports supply-chain control and consistent product quality. The company's portfolio extends beyond fillers into skincare brands in some markets, but its global reputation rests primarily on the Revanesse line and its performance in everyday aesthetic practice.

Prollenium Medical Technologies at a Glance

• Parent company: Prollenium Medical Technologies Inc., privately held, Canada-based.
• Founded: 2002 in Ontario, Canada by Ario Khoshbin.
• Headquarters: Ontario, Canada (with Revanesse marketed in North America, the UK, and other regions).
• Primary aesthetic products: Revanesse Versa/Versa+, Revanesse Lips+, Revanesse Ultra, and related HA filler SKUs.
• Market position: Specialist HA filler manufacturer and only HA filler producer in North America.
• Focus: Research, design, manufacture, and distribution of implantable hyaluronic acid polymers for aesthetic injection.
• Geographic reach: Revanesse products are available in the US, Canada, UK, and additional global markets via distributor networks.

What Is Prollenium Known For?

Prollenium has built its reputation as a pure-play injectable aesthetics company, concentrating on HA dermal fillers rather than a broad pharmaceutical portfolio. This narrow focus allows the company to dedicate R&D, manufacturing, and provider support entirely to optimizing filler performance and patient outcomes.

The Revanesse line is especially recognized for its smooth, homogeneous gel structure, achieved through proprietary production methods designed to minimize swelling and downtime while delivering natural-looking volume and contour. Many practices highlight the brand's emphasis on small-batch manufacturing, rigorous quality testing, and individually inspected syringes as differentiators that resonate with safety-conscious patients.

Prollenium also emphasizes patient comfort and satisfaction, with Revanesse formulations that often include lidocaine and are manufactured without animal-derived components, making them suitable for a broad range of patients. As Revanesse gains market share, it is increasingly positioned as a modern alternative to legacy HA fillers for clinics that want both performance and competitive economics.

What Brands Does Prollenium Own?

Prollenium organizes its aesthetic offerings around the Revanesse family of HA dermal fillers, along with complementary skincare and biorevitalization lines in some markets. The Revanesse portfolio includes products such as Versa/Versa+, Lips+, Ultra, and additional region-specific SKUs formulated for different depths and indications.

Outside injectables, Prollenium has been associated with skincare brands like Alyria and Phiderma in certain territories, focusing on medical-grade topical regimens that complement in-office treatments. However, for most US med spas and aesthetic clinics, the core relationship with Prollenium centers on Revanesse injectables for facial rejuvenation and contouring.

Revanesse Products List

Prollenium's Revanesse lineup centers on hyaluronic acid fillers that cover nasolabial folds, marionette lines, lips, and other facial areas where soft-tissue volume restoration is needed. Understanding the distinctions between products like Versa, Versa+, Lips+, and Ultra helps you build treatment protocols tailored to specific patient needs and anatomical zones.

Injectable Hyaluronic Acid Fillers

The Revanesse family is a line of cross-linked HA dermal fillers designed for facial wrinkles, folds, and volume enhancement, produced using advanced manufacturing to achieve a smooth, uniform gel. Revanesse products are indicated for adult patients (typically 22 and older in FDA-labeled uses) who want non-surgical facial rejuvenation with predictable, reversible results.

Dermal Fillers: Versa / Versa+

Revanesse Versa (and Versa+) is Prollenium's flagship mid-dermal hyaluronic acid filler for moderate to severe facial wrinkles and folds, such as nasolabial folds. The product uses a slightly larger 1.2 mL syringe compared with many competitors' 1.0 mL syringes, reducing the number of syringes required per treatment session and improving perceived value.

Clinical experience and patient-reported data suggest that Revanesse Versa typically delivers results lasting about 6–12 months, with some sources citing FDA data that support durability up to roughly 9–12 months depending on the area treated and patient metabolism. Injection sessions usually take under an hour, with immediate volumizing visible and optimal appearance often seen within 1–2 weeks as mild swelling resolves.

Dermal Fillers: Lips+

Revanesse Lips+ is formulated specifically for lip augmentation and peri-oral rejuvenation, and is FDA-approved for adults 22 years and older. The product is designed to provide smooth, natural-looking lip volume and definition with a soft, moldable gel that integrates well into delicate lip tissue.

Clinical studies submitted for FDA review followed patients for approximately six months after treatment, with many patients maintaining aesthetically pleasing results over that period and beyond. As with other HA fillers, Lips+ can be dissolved with hyaluronidase if needed, offering a significant safety and reversibility advantage in such a visible treatment area.

Dermal Fillers: Ultra And Other SKUs

Outside the US, the Revanesse range includes additional formulations such as Ultra and various "+" products that differ in HA concentration and cross-linking to target deeper folds or more structural volumization. These fillers can be used for midface contour, chin and jawline refinement, and other indications where more robust support is desired.

All products share Prollenium's core manufacturing principles: state-of-the-art production methods, premium ingredients, and thorough quality testing on every batch. This consistency allows clinics to build a comprehensive filler menu using a single brand while tailoring gel characteristics to each treatment zone.

What Does Prollenium Make? Top Revanesse Products Overview

Revanesse Versa / Versa+

Revanesse Versa (and its lidocaine-containing version Versa+) is Prollenium's central HA filler offering for correcting moderate to severe facial wrinkles and folds, including nasolabial folds. The filler's smooth, homogenous particle structure is engineered to reduce swelling and provide natural integration into the tissue.

Key details for Versa/Versa+:

• Typical patient cost: Approximately $500–$700 per syringe in many US med spas, with some clinics advertising promotional pricing around $349–$600 per 1.2 mL syringe, depending on market and offer structure.
• Duration: Commonly reported longevity of around 6–12 months, with some sources noting FDA-supported durability close to a year for many patients.
• Clinical use: Treatment of nasolabial folds and other facial wrinkles, as well as off-label use in additional facial areas depending on provider judgment.
• Key differentiator: 1.2 mL syringe size and proprietary cross-linking that aims to provide smooth, consistent gel with reduced post-injection swelling.
• Reversibility: As a hyaluronic acid filler, Versa can be dissolved with hyaluronidase in the event of overcorrection or complications.

Revanesse Lips+

Revanesse Lips+ is tailored for lip volume and contour, providing structure and definition while maintaining softness and flexibility needed for natural expression. The product contains lidocaine for improved patient comfort and uses the same quality-controlled HA technology as the rest of the Revanesse line.

Typical profile for Lips+:

• Typical patient cost: Often positioned similarly to Versa, with many practices charging in the $500–$700 per syringe range, though localized promotional pricing can vary.
• Duration: Clinical data indicate results lasting roughly 6–12 months, though high-mobility areas like the lips may metabolize filler more quickly in some patients.
• Indication: FDA-approved specifically for lip augmentation and peri-oral area enhancement in adults over 22 years old.
• Key advantage: Formulated for smooth integration and natural movement in the lips, with patient satisfaction often driven by soft, non-lumpy results.

Revanesse Ultra (Non-US And Expanding Markets)

Revanesse Ultra is a higher-density HA filler in the Revanesse family, often used internationally for deeper folds and more pronounced volume restoration. It is designed to provide additional structural support in areas such as the midface and deeper nasolabial folds, where robust lifting capacity is required.

Key aspects of Ultra:

• Use cases: Deeper facial wrinkles and folds, structural volumization, and facial contouring, depending on regulatory labeling in each market.
• Duration: Similar to or slightly longer than mid-dermal Revanesse fillers in many patients, with outcomes strongly influenced by placement, volume, and individual metabolism.
• Technology: Utilizes cross-linked HA and stringent Prollenium manufacturing standards to deliver a cohesive gel suitable for more demanding applications.

Revanesse Products Price List: Wholesale vs. Retail Pricing

As with other HA dermal fillers, your economics on Revanesse depend on the spread between wholesale acquisition cost and patient-facing pricing in your local market. Understanding this spread is critical when deciding whether to adopt or expand the line in your clinic. For a broader look at structuring your med spa menu and pricing, see our comprehensive guide.

What Clinics Pay (Wholesale)

• Revanesse Versa / Versa+: Industry pricing data for HA fillers indicate typical wholesale costs around $240–$350 per syringe, depending on the specific product, purchase volume, and distributor agreements.
• Revanesse Lips+: Usually priced in line with other premium HA fillers, with actual clinic cost influenced by bundled contracts, rewards programs, and national group purchasing power.
• Revanesse Ultra and other SKUs: International wholesale pricing varies by region and local distribution structures but generally tracks the premium HA filler segment in each market.

What Patients Pay (Typical Retail)

• Revanesse Versa / Versa+: Most US med spas advertise per-syringe pricing in the $500–$700 range, with some clinics using promotional or "membership" pricing as low as roughly $349 per syringe for limited-time offers.
• Revanesse Lips+: Often priced comparably to Versa in the same practice, with per-syringe rates typically between $500 and $700, adjusted for geography and provider positioning.
• Other Revanesse fillers: Where available, deeper-structure fillers are usually priced at a small premium over standard mid-dermal products due to higher HA content or specialized indications.

If your Revanesse wholesale price averages $280 per syringe and you charge $600 to patients, your gross margin is $320 per syringe before factoring in injector time and overhead. Higher purchase volumes and access to manufacturer or group-negotiated tiers can significantly improve margins, which is why many clinics work with partners that consolidate purchasing power.

Are Revanesse Products FDA Approved?

Running an aesthetic clinic requires a clear understanding of the regulatory status for injectable products. Revanesse products used in the US carry specific FDA approvals for defined indications and age ranges.

FDA Approval Status

• Revanesse Versa: Received Premarket Approval (PMA) in August 2017 for the cosmetic treatment of moderate to severe facial wrinkles and folds, including nasolabial folds, in adults.
• Revanesse Ultra: Cleared for the treatment of facial wrinkles, with labeling varying by market and indication.
• Revanesse Lips+: FDA-approved for lip augmentation and rejuvenation in adults 22 years and older.

These approvals reflect evidence that Revanesse fillers meet FDA standards for safety and efficacy, with comparative studies showing non-inferiority to other established HA filler brands. As with other injectables, providers should review full prescribing information and device documentation before offering treatments.

Practitioner Licensing Requirements

Licensing and scope of practice for filler injections are determined at the state or provincial level and typically follow patterns similar to other HA filler brands. For comprehensive medical oversight and compliance guidance, Portrait Care provides support, including medical director matching and regulatory resources. In most US jurisdictions:

• Injectable fillers must be administered by licensed medical professionals such as physicians, nurse practitioners, or physician assistants, often under physician supervision and within defined protocols.
• Registered nurses may inject under delegated authority in many states, provided appropriate training, oversight, and clinic policies are in place.

Internationally, regulations vary, but clinics should always ensure that injectors meet local licensing standards and that informed consent and documentation align with best-practice guidelines.

How Long Do Revanesse Filler Results Last?

While individual results vary based on metabolism, the area treated, and injection technique, Revanesse fillers fall within the same longevity range as other modern HA products.

Approximate duration by product:

• Revanesse Versa / Versa+: Commonly lasts about 6–12 months, with some FDA and clinical data indicating durability of roughly 1 year in many patients.
• Revanesse Lips+: Typically in the 6–12 month range, recognizing that high-motion areas like the lips can shorten perceived longevity.
• Revanesse Ultra and other deeper fillers: Often designed for longer-lasting support, with many patients experiencing benefit beyond 12 months, depending on treatment area and volume used.

Most patients see initial results immediately after injection, with optimal appearance emerging over 1–2 weeks as mild swelling resolves. Maintenance treatments, one to two times per year, are common to preserve results and fine-tune the contour.

Revanesse Reviews: Pros, Cons, and Best Fit

Advantages of Revanesse Products

• Modern HA technology: Revanesse fillers use refined, homogeneous gel structures and proprietary cross-linking to achieve smooth integration, natural feel, and reduced post-treatment swelling.
• Larger syringe volume: Versa's 1.2 mL syringe can increase per-syringe value, potentially reducing the number of syringes needed compared with some 1.0 mL competitors for specific indications.
• Strong safety profile: FDA approvals for Versa, Ultra, and Lips+ confirm that these fillers met rigorous clinical standards, with studies demonstrating non-inferiority to established brands.
• Reversibility: As HA fillers, Revanesse products can be dissolved with hyaluronidase, an important safety and risk-management advantage.
• Focused expertise: Prollenium's specialization in HA fillers and its status as the only HA filler manufacturer in North America enhance quality control and supply stability.

Disadvantages of Revanesse Products

• Lower consumer brand recognition: Compared with legacy names like JUVÉDERM, Restylane, or BOTOX, Revanesse may have less direct-to-consumer awareness, requiring the practice to provide more patient education.
• Narrower portfolio compared to multinational competitors: While the Revanesse line covers core indications, some competitors offer more SKUs tuned to particular anatomical zones and rheological profiles.
• Variable pricing visibility: Because Revanesse is still scaling in some markets, retail pricing can vary widely, requiring clinics to benchmark local competitors when carefully positioning their own fees.
• Training access depends on geography: While Prollenium and distributors offer training and certification opportunities, availability may be more concentrated in major metro areas than in larger global brands' event networks.

Best Fit for Revanesse Products

Revanesse products are a strong fit for:

• Practices seeking a modern HA filler line with smooth integration and a value-oriented 1.2 mL syringe format.
• Clinics that want reversible fillers backed by FDA approvals but also desire differentiation from more ubiquitous brands.
• Providers prioritize natural-looking outcomes with minimal swelling, especially for first-time filler patients or those concerned about downtime.
• Multi-location or growth-focused practices that can benefit from group purchasing arrangements and consistent HA technology across multiple facial zones.

Revanesse may be less ideal for:

• Practices where patients primarily request JUVÉDERM or Restylane by name and are resistant to trying alternative brands.
• Clinics seeking the broadest possible menu of filler rheologies and niche indications from a single manufacturer.
• Providers firmly focused on non-HA biostimulatory fillers (such as CaHA or PLLA) rather than volumizing HA products.

Alternatives to Revanesse Products

Choosing a filler portfolio involves balancing brand recognition, clinical preference, and economics. Several prominent HA and non-HA options compete with Revanesse across indications. For a detailed comparison of the most popular alternatives, see our guide on Restylane vs. Juvéderm.

Injectable Alternatives

• JUVÉDERM Collection (Allergan/AbbVie): A broad family of HA fillers using VYCROSS and Hylacross technologies, widely recognized and heavily marketed to consumers.
• Restylane Collection (Galderma): One of the oldest HA filler families, with more than two decades of data and multiple formulations for fine lines, midface, and structural contouring.
• RHA Collection (Revance): A newer group of "resilient" HA fillers that aim to maintain results during facial movement, often positioned as premium options in dynamic areas.
• Sculptra (poly-L-lactic acid) and CaHA fillers: Non-HA options that work through biostimulation rather than immediate HA volume alone, used for global volumization and collagen stimulation.

Why Practitioners Choose Alternatives

Brand awareness can drive patient demand, with some individuals seeking JUVÉDERM or Restylane by name through consumer marketing and word of mouth. Some injectors also have strong familiarity with specific rheological profiles and the training pathways offered by larger companies, which influences comfort and product choice.

In addition, exclusive or volume-based contracts with major manufacturers can shape a clinic's filler menu by tying pricing tiers, co-op marketing, and education benefits to product commitment. Many practices ultimately adopt a hybrid model, using Revanesse alongside other brands to match patient expectations and clinical nuances.

How to Choose the Right Products

Step 1: Define Your Clinical Niche

Clarify who you serve and which procedures drive your revenue: are you a general med spa, an injectables-only practice, or a facial-plastics-led clinic with advanced contouring services? If much of your volume centers on nasolabial folds and lips, a focused HA portfolio like Revanesse can efficiently cover your core indications.

Consider whether your patients prioritize "brand name" products or are open to trying newer options when guided by a trusted provider. Your branding, patient education materials, and consultation style should match your product strategy.

Step 2: Evaluate Your Practice Economics

Map out your per-syringe costs, typical treatment volumes, and target profit margins for filler services. For example, if you pay $280 for a Revanesse Versa syringe and charge $600, your gross margin is $320 before considering time and overhead; repeat visits and package pricing can further optimize lifetime value.

Compare margins across brands, factoring in rewards programs, rebates, and group purchasing opportunities that can lower net cost. Also consider patient willingness to pay in your local market: urban practices in high-cost coastal cities may sustain higher per-syringe pricing than smaller markets with more price-sensitive clientele.

Step 3: Assess Market Demand in Your Geography

Research competing clinics' filler menus and advertised pricing in your neighborhood or city. If most competitors only list JUVÉDERM and Restylane, positioning Revanesse as a modern, value-forward alternative can differentiate your practice—especially if you pair it with compelling before-and-after photography and clear education about syringe volume and gel technology.

Conversely, in markets where Revanesse is already common, patients may perceive the brand as a familiar standard, reinforcing your decision to align with regional expectations.

Step 4: Consider Training and Support

Evaluate the training infrastructure available for any filler line you bring into your practice. Prollenium and its distributor partners provide education on injection techniques, safety protocols, and patient assessment, but event frequency and geographic coverage may differ from those of larger multinationals.

Additionally, consider external training from independent academies or national conferences that emphasize safe HA injection and complication management across brands. Robust training increases provider confidence and improves patient outcomes, regardless of specific filler selection.

Step 5: Test Before Committing

Introduce Revanesse gradually by starting with core indications, such as nasolabial folds and lips, and track patient satisfaction and retention compared with your legacy fillers. Monitor for swelling, bruising, and the need for hyaluronidase reversal to validate your experience against published data.

Use your practice management or EHR tools to analyze revenue per syringe, time per procedure, and rebooking rates. Data-driven evaluation helps determine whether Revanesse should become a mainstay or remain a complementary option.

Step 6: Build Your Product Mix

Once you understand performance and economics, construct a product mix that balances patient demand, injector preference, and margin targets. Many clinics select one or two primary HA lines, plus a biostimulatory filler or specialty product, to address edge cases and niche indications.

Adding medical-grade skincare that supports in-office filler results can further increase average revenue per patient and reinforce long-term relationships. This comprehensive approach positions your clinic as a solutions provider rather than just a product dispenser.

Buy Revanesse Products with Portrait Care

Your purchasing and operations strategy strongly influences whether HA fillers generate healthy profits or strain your cash flow. Consolidating procurement through a partner that brings technology, services, and national buying power together can significantly shift your economics in favor of growth.

Portrait Care offers a platform that combines end-to-end clinic software, medical oversight services, and national pricing power across injectables and other medical supplies. This structure enables med spas and wellness clinics to access competitive filler pricing, implement standing orders, and integrate inventory with scheduling and financial reporting in one system.

Portrait Care offers:

• Tiered pricing and national-scale purchasing power for injectables and other core products.
• Bulk discounts and standing order programs to stabilize supply and support predictable monthly filler volume.
• Software tools for online booking, inventory tracking, and financial analytics, reducing administrative burden and manual errors. See our comparison of the best med spa management software for more details.
• Medical oversight and compliance services to help ensure filler treatments comply with regulatory and safety best practices.
• Strategic support for building a product mix and menu that matches patient demand while protecting margins.

Whether you are launching a new injectables clinic or scaling an existing aesthetics brand, pairing Revanesse fillers with Portrait's pricing power and operational infrastructure can help you deliver high-quality results while maintaining healthy profit margins. 

Speak to Portrait Care today.

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