‍Key Takeaways

• Core product platform: Janlane second-generation hyaluronic acid dermal fillers from Shanghai Haohai Biological Technology, designed specifically for dynamic facial filling and expression lines.
• Chinese HA and biotech leader: Haohai Biological Technology is a leading PRC biomedical materials company with strong positions in ophthalmology, orthopedics, anti-adhesion/hemostasis, and medical aesthetics, built around medical-grade sodium hyaluronate.
• Regenerative and "integrated aesthetics" focus: Haohai combines hyaluronic-acid filler families like Matrifill, Janlane, and Hyalumatrix with photoelectric (RF/laser) devices and biological agents to deliver full-cycle skin health and anti-aging programs.
• Typical positioning and pricing: Analyst and wholesale reports indicate Janlane as a second-generation, premium HA filler in Haohai's portfolio, with pricing typically benchmarked to other high-end HA dermal fillers in regional markets, differentiated by its "dynamic filling" profile.

About Shanghai Haohai Biological Technology 

Shanghai Haohai Biological Technology Co., Ltd. is a China-based biomedical materials company listed in Hong Kong, focusing on medical-grade sodium hyaluronate and related biomaterials. They have four core business areas: ophthalmology, medical aesthetics and wound care, orthopedics, and anti-adhesion and hemostasis products, underpinned by independent R&D and vertical integration.

The company holds hundreds of patents and is actively building an "integrated aesthetics" strategy—combining hyaluronic-acid fillers, photoelectric devices, and biological agents to deliver full-cycle skin-health programs that span clinic, lifestyle, and at-home scenarios. This positions Haohai as both a supplier of injectable biomaterials and a broader aesthetics platform provider in China's fast-growing cosmetic market.

Haohai Aesthetics At A Glance

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What Is Janlane? 

Janlane is Haohai's second-generation hyaluronic acid dermal filler and China's first "dynamic filling" cross-linked HA explicitly designed for facial expression curves. It uses a proprietary LTDT (low temperature secondary crosslinking) process to build a softer, purer 4D network structure that more closely mimics human skin's viscoelasticity, aiming for gentler, more vivid, and more natural facial expressions after injection.

In Haohai's overall filler family, Matrifill is designed for static contour shaping (e.g., structural support areas such as the chin and cheeks), while Janlane—with a higher dynamic viscosity—is optimized for dynamic regions and expression-related lines. This complementary positioning lets practitioners pair Matrifill for sculpting with Janlane for soft, flexible filling to achieve a balanced aesthetic outcome.

Haohai Filler Product Hierarchy

Technical Features And Indications

Janlane is a hyaluronic acid-based injectable dermal filler that has obtained CE marking in accordance with European medical device regulations. This supports its use not only in China but also in select international markets, subject to local regulatory approvals.

Its LTDT low-temperature secondary crosslinking yields a 4D network structure that is softer and more skinlike than traditional cross-linking, which international experts cited in the article say is especially suited for:

• Dynamic facial regions, where patients want expressions to remain vivid and natural.
• Refinement of lips and periorbital areas, where a purer, softer gel is helpful.

Haohai's Aesthetics Strategy

Haohai is building "full-process micro plastic surgery solutions" that combine hyaluronic acid fillers (including Matrifill and Janlane), photoelectric devices, cooling masks, and biological agents into complete treatment journeys. The goal is to cover medical clinic, lifestyle beauty, and home-care scenarios with a unified ecosystem of biomaterials, devices, and skincare that can be tailored to different patient needs and budgets.

Bioxis tissue fillers are also being integrated into Haohai's medical aesthetics portfolio. This combination of HA fillers like Janlane with RF/laser equipment mirrors global trends toward multimodal anti-aging and positions Haohai as a comprehensive solution provider in China's aesthetics market.

Haohai’s Typical Pricing And Market Positioning

Precise per-syringe pricing for Janlane is not widely published in English-language sources, but contextual clues from Haohai's research reports and the broader market are informative. Matrifill generated rapid revenue growth, and Janlane and QST were expected to expand the portfolio into dynamic and fine-line indications, improving competitiveness against imported premium brands.

Given that Janlane is positioned as a second-generation HA dermal filler with proprietary technology and regulatory approvals from the NMPA and CE, it tends to be benchmarked in China and export markets against other higher-end HA fillers in its indication class. 

In practice, clinics often price such fillers similarly to premium international products, with per-syringe fees aligned with other top-tier HA brands in the local market, while leveraging Janlane's "dynamic filling" narrative to differentiate the value proposition.

Buy Haihao Biological Products with Portrait Care 

For clinics outside China, Janlane itself may be less accessible than Western and European brands. Still, the strategic questions remain the same: where does a second-generation, dynamic HA filler fit in your portfolio, and how do you make it profitable? 

Portrait's approach to injectables, detailed in its dermal fillers and biostimulators services overview, focuses on:

• Tiered pricing and volume-based discounts up to 60% to reduce per-syringe acquisition cost.
• Centralized ordering and inventory controls that match stock levels to actual procedure volume.
• Product-mix planning that balances "workhorse" fillers with specialized products like dynamic or fine-line-specific fillers.

Lean on Portrait Care for procuring Haihao Biological Products. Speak to Portrait Care today.

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